Zhengdeng Lei, PhD
Zhengdeng Lei, PhD
2007 - 2009 High Throughput Computational Analyst, Memorial Sloan-Kettering Cancer Center, New York
2003 - 2007 PhD, Bioinformatics, University of Illinois at Chicago
Tuesday, February 21, 2012
Tuesday, February 14, 2012
Sunday, February 12, 2012
limma anova
http://www.statsci.org/smyth/pubs/limma-biocbook-reprint.pdf
http://bioconductor.org/packages/2.6/bioc/vignettes/limma/inst/doc/usersguide.pdf
https://stat.ethz.ch/pipermail/bioconductor/2006-August/013998.html
http://www.bioconductor.org/help/course-materials/2009/BioC2009/labs/limma/limma.pdf
KO <- factor(rep(1:2, each = 3, times = 2))
CELL <- factor(rep(1:2, each = 6))
design <- model.matrix(~KO + CELL)
In R:
> mat <- cbind(c(1,1,1,rep(0,9)),
+ c(0,0,0,1,1,1,rep(0,6)),
+ c(rep(0,6),1,1,1,0,0,0),
+ c(rep(0,9),1,1,1))
> colnames(mat) <- c("nu","nt","tu","tt")
http://bioconductor.org/packages/2.6/bioc/vignettes/limma/inst/doc/usersguide.pdf
https://stat.ethz.ch/pipermail/bioconductor/2006-August/013998.html
http://www.bioconductor.org/help/course-materials/2009/BioC2009/labs/limma/limma.pdf
KO <- factor(rep(1:2, each = 3, times = 2))
CELL <- factor(rep(1:2, each = 6))
design <- model.matrix(~KO + CELL)
In R:
> mat <- cbind(c(1,1,1,rep(0,9)),
+ c(0,0,0,1,1,1,rep(0,6)),
+ c(rep(0,6),1,1,1,0,0,0),
+ c(rep(0,9),1,1,1))
> colnames(mat) <- c("nu","nt","tu","tt")
Thursday, February 9, 2012
Solid tumors
Common three subtypes of solid tumors:
Inv, Pro, Meta
BEZ235, Nilotinib, 5-FU
Inv, Pro, Meta
BEZ235, Nilotinib, 5-FU
Monday, February 6, 2012
Thursday, February 2, 2012
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