Zhengdeng Lei, PhD

Zhengdeng Lei, PhD

2009 - Present Research Fellow at Duke-NUS, Singapore
2007 - 2009 High Throughput Computational Analyst, Memorial Sloan-Kettering Cancer Center, New York
2003 - 2007 PhD, Bioinformatics, University of Illinois at Chicago

Tuesday, December 13, 2011

http://www.youtube.com/watch?v=VwZWa76vKFE

http://www.youtube.com/watch?v=VwZWa76vKFE

Monday, November 28, 2011

Ranking

http://ontario.compareschoolrankings.org/elementary/SchoolsByAreaMap.aspx
http://ontario.compareschoolrankings.org/secondary/SchoolsByAreaMap.aspx

Saturday, November 26, 2011

http://www.imuc.com/pdf/Griffin-Industry-Report-09-14-2009.pdf

http://www.imuc.com/pdf/Griffin-Industry-Report-09-14-2009.pdf

Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739007/


Breast CS CD44+/CD24-/Lin-
Prospective identification of tumorigenic breast cancer cells

Friday, November 25, 2011

BEZ235 vs CD44+


Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma


Results: Here, we show that inhibition of PI3K activity by the dual PI3K/mTOR inhibitor NVP-BEZ235 leads to a decrease in the population of CD133+/CD44+ prostate cancer progenitor cells in vivo. Moreover, the combination of the PI3K/mTOR modulator NVP-BEZ235, which eliminates prostate cancer progenitor populations, and the chemotherapeutic drug Taxotere, which targets the bulk tumor, is significantly more effective in eradicating tumors in a prostate cancer xenograft model than monotherapy.

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

http://www.cell.com/retrieve/pii/S0092867409007818