GSAA

High, mid, low activity, e.g. p53
mid vs low -->(GSEA)  ES
high vs low --> High ES??

Supposed we have 200 cell lines, obtain the expression before drug treatment, and obtain GI50 for M drugs.

(NCI60, too small?)

	Drug1	Drug2	Drug3	... ...	DrugM
GeneSet1	Corr(1,1) = GSAA1vsGI50 for drug 1 across all cell lines	Corr(1,2) = GSAA1vsGI50 for drug2 across all cell lines
GeneSet2
GeneSet3
GeneSet4
... ...
GeneSetN