Zhengdeng Lei, PhD

Zhengdeng Lei, PhD

2009 - Present Research Fellow at Duke-NUS, Singapore
2007 - 2009 High Throughput Computational Analyst, Memorial Sloan-Kettering Cancer Center, New York
2003 - 2007 PhD, Bioinformatics, University of Illinois at Chicago

Thursday, June 14, 2012

Overlap of gene signatures of GC and PDA

1. Inv overlap signature_GC and signature_PDA, then DAVID/Gather


KEGG Pathway# Genesp ValueBayes Factor
1.path:hsa04010: MAPK signaling pathway19[show]      0.0051

2.path:hsa04020: Calcium signaling pathway16[show]      0.0071

3.path:hsa04210: Apoptosis10[show]     0.0071

4.path:hsa04610: Complement and coagulation cascades8[show]     0.010




Gene Ontology# Genesp ValueBayes Factor
1.GO:0007154 [3]: cell communication156[show]          < 0.000115
2.GO:0007275 [2]: development88[show]          < 0.00019
3.GO:0007165 [4]: signal transduction123[show]          < 0.00018
4.GO:0009653 [3]: morphogenesis62[show]          < 0.00018
5.GO:0009887 [4]: organogenesis52[show]          < 0.00017
6.GO:0048513 [3]: organ development52[show]          < 0.00017
7.GO:0006956 [6]: complement activation8[show]         0.00025
8.GO:0007242 [5]: intracellular signaling cascade50[show]        0.00064


2. Pro


KEGG Pathway# Genesp ValueBayes Factor
1.path:hsa04110: Cell cycle16[show]          < 0.000111
2.path:hsa04080: Neuroactive ligand-receptor interaction2[show]       0.0012
3.path:hsa00100: Biosynthesis of steroids4[show]     0.0071



Gene Ontology# Genesp ValueBayes Factor
1.GO:0000278 [6]: mitotic cell cycle35[show]          < 0.000136
2.GO:0007067 [8]: mitosis29[show]          < 0.000135
3.GO:0000087 [7]: M phase of mitotic cell cycle29[show]          < 0.000135
4.GO:0000279 [6]: M phase32[show]          < 0.000133
5.GO:0000280 [7]: nuclear division31[show]          < 0.000133
6.GO:0007049 [5]: cell cycle62[show]          < 0.000130
7.GO:0008283 [4]: cell proliferation73[show]          < 0.000124
8.GO:0000910 [5]: cytokinesis18[show]          < 0.000114


3.Meta


KEGG Pathway# Genesp ValueBayes Factor
1.path:hsa00480: Glutathione metabolism3[show]         0.00025
2.path:hsa00260: Glycine, serine and threonine metabolism2[show]      0.0032
3.path:hsa00791: Atrazine degradation1[show]      0.0041
4.path:hsa00460: Cyanoamino acid metabolism1[show]     0.0071
5.path:hsa00430: Taurine and hypotaurine metabolism1[show]     0.0091
6.path:hsa00625: Tetrachloroethene degradation1[show]     0.0091
7.path:hsa00363: Bisphenol A degradation1[show]     0.010




Gene Ontology# Genesp ValueBayes Factor
1.GO:0007586 [4]: digestion3[show]       0.0013
2.GO:0008203 [7]: cholesterol metabolism3[show]       0.0013
3.GO:0016125 [6]: sterol metabolism3[show]       0.0013
4.GO:0006848 [8]: pyruvate transport1[show]      0.0052
5.GO:0007039 [7]: vacuolar protein catabolism1[show]      0.0052
6.GO:0007165 [4]: signal transduction3[show]     0.011
7.GO:0045494 [8]: photoreceptor maintenance1[show]     0.011
8.GO:0006621 [6]: protein-ER retention1[show]     0.011




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